Targeting Glial Cells by Organic Anion-Transporting Polypeptide 1C1 (OATP1C1)-Utilizing <scp>l</scp>-Thyroxine-Derived Prodrugs-Reference-Cited by-同舟云学术

Targeting Glial Cells by Organic Anion-Transporting Polypeptide 1C1 (OATP1C1)-Utilizing l-Thyroxine-Derived Prodrugs

Published:2023-11-06 Issue:22 Volume:66 Page:15094-15114
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tonduru Arun Kumar¹^ORCID,Maljaei Seyed Hamed¹,Adla Santosh Kumar¹^ORCID,Anamea Landry¹,Tampio Janne¹^ORCID,Králová Adéla¹,Jalkanen Aaro J.¹,Espada Catarina¹,Santos Inês Falcato¹,Montaser Ahmed B.¹^ORCID,Rautio Jarkko¹,Kronenberger Thales¹²³,Poso Antti¹²³⁴⁵^ORCID,Huttunen Kristiina M.¹^ORCID

Affiliation:

1. School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland

2. Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard-Karls-Universität, Tuebingen, Auf der Morgenstelle 8, 72076 Tuebingen, Germany

3. Tuebingen Center for Academic Drug Discovery & Development (TüCAD2), 72076 Tuebingen, Germany

4. Department of Internal Medicine VIII, University Hospital Tübingen, DE 72076 Tübingen, Germany

5. Cluster of Excellence iFIT (EXC 2180) “Image-Guided and Functionally Instructed Tumor Therapies”, University of Tübingen, 72076 Tübingen, Germany

Funder

Bundesministerium f?r Bildung und Forschung

Sigrid Jus?liuksen S??ti?

Terveyden Tutkimuksen Toimikunta

European Proteomics Infrastructure Consortium providing access

Ministerium f?r Wissenschaft, Forschung und Kunst Baden-W?rttemberg

Horizon 2020 Framework Programme

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01026

Reference60 articles.

1. Identification of a Novel Human Organic Anion Transporting Polypeptide as a High Affinity Thyroxine Transporter

2. Single-cell transcriptome profiling of thyroid hormone effectors in the human fetal neocortex: expression of SLCO1C1, DIO2, and THRB in specific cell types

3. Detection and treatment of congenital hypothyroidism

4. Expression of the Thyroid Hormone Transporters Monocarboxylate Transporter-8 (SLC16A2) and Organic Ion Transporter-14 (SLCO1C1) at the Blood-Brain Barrier

5. Mutated Thyroid Hormone Transporter OATP1C1 Associates with Severe Brain Hypometabolism and Juvenile Neurodegeneration

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Improving drug delivery to the brain: the prodrug approach;Expert Opinion on Drug Delivery;2024-05-03