Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5′-UTR RNA G-Quadruplexes-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5′-UTR RNA G-Quadruplexes

Published:2024-01-25 Issue:3 Volume:67 Page:1961-1981
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Mao-Lin¹,Dai Le-Tian¹,Gao Zhuo-Yu¹,Yan Jia-Tong¹,Xu Shu-Min¹,Tan Jia-Heng¹^ORCID,Huang Zhi-Shu¹^ORCID,Chen Shuo-Bin¹^ORCID,Chen Xiu-Cai¹²^ORCID

Affiliation:

1. School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Sun Yat-sen University, Guangzhou, Guangdong 510006, China

2. School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, Guangdong 510006, China

Funder

Changjiang Scholar Program, Ministry of Education

Basic and Applied Basic Research Foundation of Guangdong Province

Guangdong Provincial Key Laboratory of Construction Foundation

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01773

Reference45 articles.

1. ras GENES

2. RAS Proteins and Their Regulators in Human Disease

3. Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

4. Molecular Switch for Signal Transduction: Structural Differences Between Active and Inactive Forms of Protooncogenic ras Proteins

5. The ERK Cascade: Distinct Functions within Various Subcellular Organelles

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP