Discovery of Highly Potent Pinanamine-Based Inhibitors against Amantadine- and Oseltamivir-Resistant Influenza A Viruses-Reference-Cited by-同舟云学术

Discovery of Highly Potent Pinanamine-Based Inhibitors against Amantadine- and Oseltamivir-Resistant Influenza A Viruses

Published:2018-05-25 Issue:12 Volume:61 Page:5187-5198
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhao Xin¹²³^ORCID,Li Runfeng⁴,Zhou Yang⁵,Xiao Mengjie¹²,Ma Chunlong³⁶,Yang Zhongjin¹,Zeng Shaogao²,Du Qiuling⁴,Yang Chunguang⁴,Jiang Haiming⁴,Hu Yanmei³⁶,Wang Kefeng¹,Mok Chris Ka Pun⁴⁷,Sun Ping¹,Dong Jianghong²,Cui Wei²,Wang Jun³⁶^ORCID,Tu Yaoquan⁵,Yang Zifeng⁴,Hu Wenhui¹²

Affiliation:

1. State Key Laboratory of Respiratory Disease, Key Laboratory of Molecular Target & Clinical Pharmacology, School of Pharmaceutical Sciences & The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, P. R. China

2. Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, P. R. China

3. Department of Pharmacology and Toxicology, College of Pharmacy, The University of Arizona, Tucson, Arizona 85721, United States

4. State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou 510120, P. R. China

5. Division of Theoretical Chemistry and Biology, School of Biotechnology, Royal Institute of Technology (KTH), AlbaNova University Center, Stockholm SE-100 44, Sweden

6. BIO5 Institute, The University of Arizona, Tucson, Arizona 85721, United States

7. HKU-Pasteur Research Pole, School of Public Health, HKU Li Ka Shing Faculty of Medicine, The University of Hong Kong, 5 Sassoon Road, Pokfulam, Hong Kong

Funder

Food and Health Bureau

Ministry of Science and Technology of the People's Republic of China

Guangzhou Medical University

U.S. Department of Health and Human Services

Youth Innovation Promotion Association of the Chinese Academy of Sciences

China Scholarship Council

National Natural Science Foundation of China

State Key Laboratory of Respiratory Disease, Guangzhou Medical University

Guangzhou Municipality

Swedish Infrastructure Committee

Guangdong Province