Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform NaV1.7-Reference-Cited by-同舟云学术

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Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform NaV1.7

Published:2019-04-23 Issue:19 Volume:62 Page:8695-8710
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mulcahy John V.¹^ORCID,Pajouhesh Hassan¹,Beckley Jacob T.²,Delwig Anton¹,Du Bois J.³^ORCID,Hunter John C.¹

Affiliation:

1. SiteOne Therapeutics, 280 Utah Avenue, Suite 250, South San Francisco, California 94080, United States

2. SiteOne Therapeutics, 351 Evergreen Drive, Suite B1, Bozeman, Montana 59715, United States

3. Lokey Chemistry and Biology, Stanford University, 337 Campus Drive, Stanford, California 94305, United States

Funder

National Institute of Neurological Disorders and Stroke

Medical Research and Materiel Command

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01906

Reference120 articles.

1. The hitchhiker’s guide to the voltage-gated sodium channel galaxy

2. International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels

3. Diversity of Mammalian Voltage-Gated Sodium Channels

4. Classification of Drugs Based on Properties of Sodium Channel Inhibition: A Comparative Automated Patch-Clamp Study

5. Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction.

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