Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model-Reference-Cited by-同舟云学术

Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model

Published:2019-01-15 Issue:3 Volume:62 Page:1306-1329
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Depauw Sabine¹^ORCID,Lambert Mélanie¹^ORCID,Jambon Samy¹^ORCID,Paul Ananya²,Peixoto Paul¹,Nhili Raja¹,Marongiu Laura¹,Figeac Martin³,Dassi Christelle¹,Paul-Constant Charles¹,Billoré Benjamin¹,Kumar Arvind²,Farahat Abdelbasset A.²,Ismail Mohamed A.²,Mineva Ekaterina²,Sweat Daniel P.⁴,Stephens Chad E.⁴,Boykin David W.²,Wilson W. David²^ORCID,David-Cordonnier Marie-Hélène¹^ORCID

Affiliation:

1. UMR-S1172-JPARC (Jean-Pierre Aubert Research Center), INSERM, University of Lille, Centre Hospitalier Universitaire de Lille, Institut pour la Recherche sur le Cancer de Lille (IRCL), F-59045 Lille, France

2. Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, United States

3. Functional and Structural Genomic Platform, Lille University, F-59000 Lille, France

4. Department of Chemistry and Physics, Augusta University, Augusta, Georgia 30904, United States

Funder

Association pour la Recherche sur le Cancer

European Commission

Association Laurette Fugain

Fondation ARC pour la Recherche sur le Cancer

Minist??re de l'Enseignement Sup??rieur et de la Recherche Scientifique

Ligue Contre le Cancer

U.S. Department of Health and Human Services

R??gion Nord-Pas de Calais