Computational Method to Evaluate Progress in Lead Optimization-Reference-Cited by-同舟云学术

Computational Method to Evaluate Progress in Lead Optimization

Published:2018-11-30 Issue:23 Volume:61 Page:10895-10900
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Vogt Martin¹,Yonchev Dimitar¹,Bajorath Jürgen¹^ORCID

Affiliation:

1. Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Endenicher Allee 19c, D-53115 Bonn, Germany

Funder

J?rgen Manchot Stiftung

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01626

Reference20 articles.

1. QSAR Modeling: Where Have You Been? Where Are You Going To?

2. Advances in multiparameter optimization methods forde novodrug design

3. Lead optimization attrition analysis (LOAA): a novel and general methodology for medicinal chemistry

4. Computational method for estimating progression saturation of analog series

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