Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer-Reference-Cited by-同舟云学术

Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer

Published:2019-01-10 Issue:2 Volume:62 Page:941-964
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Han Xin,Wang Chao,Qin Chong,Xiang Weiguo,Fernandez-Salas Ester,Yang Chao-Yie,Wang Mi,Zhao Lijie,Xu Tianfeng,Chinnaswamy Krishnapriya,Delproposto James,Stuckey Jeanne,Wang Shaomeng^ORCID

Funder

National Cancer Institute

Oncopia Therapeutics, LLC

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01631

Reference46 articles.

1. 10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer

2. The Diagnosis and Treatment of Prostate Cancer

3. Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches

4. Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion

5. Destroying the androgen receptor (AR)-potential strategy to treat advanced prostate cancer

Cited by 294 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Between Theory and Practice: Computational/Experimental Integrated Approaches to Understand the Solubility and Lipophilicity of PROTACs;Journal of Medicinal Chemistry;2024-09-13

2. Stereochemical inversion at a 1,4-cyclohexyl PROTAC linker fine-tunes conformation and binding affinity;Bioorganic & Medicinal Chemistry Letters;2024-09

3. M1/M2 macrophage-targeted nanotechnology and PROTAC for the treatment of atherosclerosis;Life Sciences;2024-09

4. PROTAC unleashed: Unveiling the synthetic approaches and potential therapeutic applications;European Journal of Medicinal Chemistry;2024-09

5. A one-pot photocatalytic triazole-based linkerology for PROTACs;Cell Reports Physical Science;2024-08