Down-Regulation of the Androgen Receptor by G-Quadruplex Ligands Sensitizes Castration-Resistant Prostate Cancer Cells to Enzalutamide-Reference-Cited by-同舟云学术

Down-Regulation of the Androgen Receptor by G-Quadruplex Ligands Sensitizes Castration-Resistant Prostate Cancer Cells to Enzalutamide

Published:2018-09-06 Issue:19 Volume:61 Page:8625-8638
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tassinari Martina¹,Cimino-Reale Graziella²,Nadai Matteo¹,Doria Filippo³,Butovskaya Elena¹,Recagni Marta²,Freccero Mauro³^ORCID,Zaffaroni Nadia²,Richter Sara N.¹^ORCID,Folini Marco²

Affiliation:

1. Department of Molecular Medicine, University of Padua, via A. Gabelli 63, 35121 Padua, Italy

2. Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Via G. A. Amadeo 42, 20133 Milan, Italy

3. Department of Chemistry, University of Pavia, v. le Taramelli 10, 27100, Pavia, Italy

Funder

Fondazione Antonio Carlo Monzino

FP7 Ideas: European Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00502

Reference75 articles.

1. Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer