Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear Factor (Erythroid-derived 2)-like 2 (NRF2) Inhibitors

Author:

Richardson Benjamin G.1ORCID,Jain Atul D.1,Potteti Haranatha R.,Lazzara Phillip R.1,David Brian P.1ORCID,Tamatam Chandra R.,Choma Ewelina1,Skowron Kornelia1,Dye Katherine,Siddiqui Zamia1,Wang Yue-Ting,Krunic Aleksej1,Reddy Sekhar P.,Moore Terry W.1ORCID

Affiliation:

1. Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, ‡Department of Pediatrics, College of Medicine, §UICentre for Drug Discovery, ⊥Mass Spectrometry Core at Research Resources Center, #University of Illinois Cancer Center, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, United States

Funder

National Heart, Lung, and Blood Institute

National Institute of Arthritis and Musculoskeletal and Skin Diseases

University of Illinois at Chicago

Michael Reese Research and Education Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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