Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer-Reference-Cited by-同舟云学术

Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer

Published:2018-12-03 Issue:24 Volume:61 Page:11280-11297
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wu Xingsen¹²,Li Xiang¹³,Li Zhihong¹²,Yu Yancheng¹²,You Qidong¹^ORCID,Zhang Xiaojin¹²^ORCID

Affiliation:

1. State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, 210009, China

2. Department of Chemistry, School of Science, China Pharmaceutical University, Nanjing, 211198, China

3. Department of Pharmaceutical Engineering, China Pharmaceutical University, Nanjing, 211198, China

Funder

Ministry of Education of the People's Republic of China

Ministry of Science and Technology of the People's Republic of China

Government of Jiangsu Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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