Discovery of β-Arrestin Biased Ligands of 5-HT7R-Reference-Cited by-同舟云学术

Discovery of β-Arrestin Biased Ligands of 5-HT7R

Published:2018-07-20 Issue:16 Volume:61 Page:7218-7233
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kim Youngjae¹²,Kim Hyunguk³,Lee Jieon¹⁴,Lee Jae Kyun¹,Min Sun-Joon⁵^ORCID,Seong Jihye¹⁴⁶,Rhim Hyewhon⁴⁷,Tae Jinsung²,Lee Hyunjoo Jenny³,Choo Hyunah¹⁴^ORCID

Affiliation:

1. Center for Neuro-Medicine, Brain Research Institute, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea

2. Department of Chemistry, Yonsei University, Seoul 03722, Republic of Korea

3. School of Electrical Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea

4. Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Republic of Korea

5. Department of Chemical & Molecular Engineering/Applied Chemistry, Hanyang University, Ansan, Gyeonggi-do 15588, Republic of Korea

6. Convergence Research Center for Diagnosis Treatment Care of Dementia, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea

7. Center for Neuroscience, Brain Research Institute, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea

Funder

National Research Foundation of Korea

Korea Institute of Science and Technology

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00642

Reference62 articles.

1. The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints

2. Introduction: G-Protein Coupled Receptors

3. Crystal structure of the β2 adrenergic receptor–Gs protein complex

4. Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

5. Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function

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