Yeast Chemogenomic Profiling Reveals Iron Chelation To Be the Principle Cell Inhibitory Mode of Action of Gossypol
Author:
Affiliation:
1. Royal Botanic Gardens, Kew, Richmond, Surrey TW9 3AB, United Kingdom
2. Developmental & Molecular Pathways, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Fabrikstrasse 22, CH-4056 Basel, Switzerland
Funder
Novartis
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00692
Reference42 articles.
1. Occurrence of (+)- and (−)-Gossypol in Wild Species of Cotton and in Gossypium hirsutum Var. marie-galante (Watt) Hutchinson
2. Growth inhibitory effects of gossypol and related compounds on fungal cotton root pathogens
3. Toxicity of (+)- and (−)-Gossypol to the Plant Pathogen, Rhizoctonia solani
4. Differential effects of the (+)- and (–)-gossypol enantiomers upon Entamoeba histolytica axenic cultures
5. Inhibitory Action of Gossypol on Enzymes and Growth of Trypanosoma cruzi
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. The nutritional and industrial significance of cottonseeds and genetic techniques in gossypol detoxification;PLANTS, PEOPLE, PLANET;2023-10-02
2. Modes‐of‐action of antifungal compounds: Stressors and (target‐site‐specific) toxins, toxicants, or toxin–stressors;Microbial Biotechnology;2023-05-16
3. A simplified and easy‐to‐use HIP HOP assay provides insights into chalcone antifungal mechanisms of action;FEBS Letters;2022-09-09
4. Deletion C-terminal thioesterase abolishes melanin biosynthesis, affects metabolism and reduces the pathogenesis of Fonsecaea monophora;PLOS Neglected Tropical Diseases;2022-06-13
5. Structure, properties of gossypol and its derivatives—from physiological activities to drug discovery and drug design;Natural Product Reports;2022
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3