Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias-Reference-Cited by-同舟云学术

Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias

Published:2018-09-10 Issue:19 Volume:61 Page:8895-8907
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kennedy Nicole M.¹²,Schmid Cullen L.²,Ross Nicolette C.¹²,Lovell Kimberly M.¹²,Yue Zhizhou¹²,Chen Yen Ting¹²,Cameron Michael D.²,Bohn Laura M.²,Bannister Thomas D.¹²^ORCID

Affiliation:

1. Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States

2. Department of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida 33458, United States

Funder

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01136

Reference32 articles.

1. Analysis of opioid efficacy, tolerance, addiction and dependence from cell culture to human

2. Pain market

3. Overdose Deaths Involving Opioids, Cocaine, and Psychostimulants — United States, 2015–2016

4. Addressing the Fentanyl Threat to Public Health

5. Current Research on Opioid Receptor Function

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