Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis-Reference-Cited by-同舟云学术

Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis

Published:2019-02-01 Issue:5 Volume:62 Page:2541-2563
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bäurle Stefan¹^ORCID,Nagel Jens¹,Peters Olaf¹,Bräuer Nico¹,ter Laak Antonius¹,Preusse Cornelia¹,Rottmann Antje¹,Heldmann Dieter¹,Bothe Ulrich¹,Blume Thorsten¹,Zorn Ludwig¹,Walter Daryl²,Zollner Thomas M.¹,Steinmeyer Andreas¹,Langer Gernot¹

Affiliation:

1. Bayer AG, Research & Development, Pharmaceuticals, Müllerstrasse 178, 13353 Berlin, Germany

2. Evotec (UK) Ltd., 112-114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01862

Reference54 articles.

1. The significant effect of endometriosis on physical, mental and social wellbeing: results from an international cross-sectional survey

2. Consensus on current management of endometriosis

3. ESHRE guideline: management of women with endometriosis

4. Endometriosis

5. Epidemiology of endometriosis: a large population-based database study from a healthcare provider with 2 million members

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Docking for EP4R antagonists active against inflammatory pain;Nature Communications;2023-12-06

2. Research advances in drug therapy of endometriosis;Frontiers in Pharmacology;2023-06-21

3. Using a Quantitative High-Throughput Screening Platform to Identify Molecular Targets and Compounds as Repurposing Candidates for Endometriosis;Biomolecules;2023-06-08

4. An Analysis of Successful Hit-to-Clinical Candidate Pairs;Journal of Medicinal Chemistry;2023-05-24

5. Green Approach toward Triazole forming Reactions for Developing Anticancer Drugs;Current Organic Synthesis;2023-05-08