Identification and Pharmacological Profile of an Indane Based Series of Ghrelin Receptor Full Agonists-Reference-Cited by-同舟云学术

Identification and Pharmacological Profile of an Indane Based Series of Ghrelin Receptor Full Agonists

Published:2018-06-17 Issue:14 Volume:61 Page:5974-5987
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gardelli Cristina^ORCID,Wada Hiroki,Ray Asim,Caffrey Moya,Llinas Antonio^ORCID,Shamovsky Igor^ORCID,Tholander Joakim¹,Larsson Joakim,Sivars Ulf,Hultin Leif²,Andersson Ulf³,Sanganee Hitesh J.⁴,Stenvall Kristina,Leidvik Brith⁵,Gedda Karin⁵,Jinton Lisa,Rydén Landergren Marie,Karabelas Kostas

Affiliation:

1. Medicinal Chemistry Department, Cardiovascular and Metabolic Diseases IMED Biotech Unit, AstraZeneca Gothenburg, 43183 Mölndal, Sweden

2. Precision Medicine Laboratories, Precision Medicine and Genomics IMED Biotech Unit, AstraZeneca Gothenburg, 43183 Mölndal, Sweden

3. Drug Safety and Metabolism IMED Biotech Unit, AstraZeneca Gothenburg, 43183 Mölndal, Sweden

4. Scientific Partnering & Alliances IMED Biotech Unit, AstraZeneca, SK10 4TF Cambridge, United Kingdom

5. Discovery Sciences IMED Biotech Unit, AstraZeneca Gothenburg, 43183 Mölndal, Sweden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00322

Reference41 articles.

1. Ghrelin-producing cells exist as two types of cells, closed- and opened-type cells, in the rat gastrointestinal tract

2. Biological, Physiological, Pathophysiological, and Pharmacological Aspects of Ghrelin

3. Treatment of Cachexia With Ghrelin in Patients With COPD

4. Randomized study of the efficacy and safety of SUN11031 (synthetic human ghrelin) in cachexia associated with chronic obstructive pulmonary disease

5. Elevated Circulating Level of Ghrelin in Cachexia Associated With Chronic Heart Failure

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