Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur-Reference-Cited by-同舟云学术

Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur

Published:2018-12-07 Issue:2 Volume:62 Page:987-992
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Dementiev Alexey¹,Joachimiak Andrzej¹,Nguyen Ha²³,Gorelik Alexei⁴,Illes Katalin⁴,Shabani Saman⁵,Gelsomino Michael⁵,Ahn Eun-Young Erin⁶,Nagar Bhushan⁴,Doan Ninh⁶^ORCID

Affiliation:

1. Structural Biology Center, Biosciences Division, Argonne National Laboratory, Lemont, Illinois 60439, United States

2. California Institute of Neuroscience, Thousand Oaks, California 91360, United States

3. National Skull Base Center, Thousand Oaks, California 91360, United States

4. Department of Biochemistry and Groupe de Recherche Axé sur la Structure des Protéines, McGill University, Montreal, Quebec H3G 0B1, Canada

5. Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States

6. Department of Neurosurgery, Mitchell Cancer Institute, University of South Alabama, Mobile, Alabama 36617 United States

Funder

U.S. Department of Energy

Musella Foundation For Brain Tumor Research and Information

Mitchell Cancer Institute, University of South Alabama Health System

Department of Neurosurgery, University of South Alabama Health System

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01723

Reference41 articles.

1. Recent studies of 5-fluorouracil resistance in pancreatic cancer

2. 5-fluorouracil and cardiotoxicity: a review

3. Efficacy of Oral Adjuvant Therapy After Resection of Colorectal Cancer: 5-Year Results From Three Randomized Trials

4. Hyperthermia enhances the in vitro activity of 1-hexylcarbamoyl-5-fluorouracil compared to that of 5-fluorouracil

5. Plasma, Intestine and Tumor Levels of 5-Fluorouracil in Mice Bearing L1210 Ascites Tumor Following Oral Administration of 5-Fluorouracil, UFT (Mixed Compound of Tegafur and Uracil), Carmofur and 5'-Deoxy-5-fluorouridine.

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