1. Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Straße 9, D-60438 Frankfurt, Germany
2. Institute of Pharmacology, College of Pharmacy, Goethe University Frankfurt, Max-von-Laue-Straße 9, D-60438 Frankfurt, Germany
3. Institute of Clinical Pharmacology, Goethe University Frankfurt, Theodor-Stern-Kai 7, D-60590 Frankfurt, Germany
4. Institute of Pharmacological Sciences, University of Milan, Via Balzaretti 9, I-20133 Milan, Italy