Novel Minor Groove Binders Cure Animal African Trypanosomiasis in an in Vivo Mouse Model

Author:

Giordani Federica,Khalaf Abedawn I.1,Gillingwater Kirsten23,Munday Jane C.,de Koning Harry P.,Suckling Colin J.1,Barrett Michael P.4,Scott Fraser J.5ORCID

Affiliation:

1. Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, Glasgow G1 1XL, U.K.

2. Parasite Chemotherapy, Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel 4051, Switzerland

3. University of Basel, Basel 4001, Switzerland

4. Glasgow Polyomics, University of Glasgow, Glasgow G61 1QH, U.K.

5. Department of Biological and Geographical Sciences, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, U.K.

Funder

Biotechnology and Biological Sciences Research Council

Merck Sharp and Dohme

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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