Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities-Reference-Cited by-同舟云学术

Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities

Published:2018-08-20 Issue:17 Volume:61 Page:7877-7891
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Qinghui¹,Arnst Kinsie E.¹,Wang Yuxi²,Kumar Gyanendra³,Ma Dejian¹,Chen Hao¹,Wu Zhongzhi¹,Yang Jinliang²,White Stephen W.³,Miller Duane D.¹^ORCID,Li Wei¹⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States

2. State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan 610041, China

3. Department of Structural Biology, St. Jude Children’s Research Hospital, Memphis, Tennessee 38105, United States

4. Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong 511436, China

Funder

National Cancer Institute

National Center for Research Resources

NIH Office of the Director

Guangzhou Municipality

College of Pharmacy, University of Tennessee Health Science Center

American Lebanese Syrian Associated Charities

Publisher

American Chemical Society (ACS)

Subject