Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections-Reference-Cited by-同舟云学术

Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections

Published:2019-03-25 Issue:8 Volume:62 Page:3989-4012
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Linciano Pasquale¹,Pozzi Cecilia²,Iacono Lucia dello²,di Pisa Flavio²,Landi Giacomo²,Bonucci Alessio²,Gul Sheraz³,Kuzikov Maria³,Ellinger Bernhard³,Witt Gesa³,Santarem Nuno⁴⁵,Baptista Catarina⁴⁵,Franco Caio⁶,Moraes Carolina B.⁶,Müller Wolfgang,Wittig Ulrike,Luciani Rosaria¹,Sesenna Antony¹,Quotadamo Antonio¹,Ferrari Stefania¹,Pöhner Ina,Cordeiro-da-Silva Anabela⁴⁵,Mangani Stefano²^ORCID,Costantino Luca¹^ORCID,Costi Maria Paola¹^ORCID

Affiliation:

1. Dipartimento di Scienze della Vita, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy

2. Dipartimento di Biotecnologie, Chimica e Farmacia, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy

3. Fraunhofer Institute for Molecular Biology and Applied Ecology Screening Port, 22525 Hamburg, Germany

4. Institute for Molecular and Cell Biology, 4150-180 Porto, Portugal

5. Instituto de Investigação e Inovação em Saúde, Universidade do Porto and Institute for Molecular and Cell Biology, 4150-180 Porto, Portugal

6. Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisaem Energia e Materiais (CNPEM), 13083-100 Campinas, São Paulo, Brazil

Funder

Klaus Tschira Stiftung

Seventh Framework Programme

Heidelberg Biosciences International Graduate School

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b02021

Reference61 articles.

1. The trypanosomiases

2. Human African trypanosomiasis

3. Chemotherapy of trypanosomiases and leishmaniasis

4. Drug resistance in human African trypanosomiasis

5. Sleeping sickness can now be cured with pills

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