Discovery of Marinoquinolines as Potent and Fast-Acting Plasmodium falciparum Inhibitors with in Vivo Activity

Author:

Aguiar Anna Caroline Campos1,Panciera Michele2,Simão dos Santos Eric Francisco2,Singh Maneesh Kumar34,Garcia Mariana Lopes1,de Souza Guilherme Eduardo1,Nakabashi Myna4,Costa José Luiz5,Garcia Célia R. S.3,Oliva Glaucius1,Correia Carlos Roque Duarte2ORCID,Guido Rafael Victorio Carvalho1ORCID

Affiliation:

1. Sao Carlos Institute of Physics, University of Sao Paulo, Av. Joao Dagnone, 1100 Jardim Santa Angelina, São Carlos, SP 13563-120, Brazil

2. Institute of Chemistry, State University of Campinas, Josue de Castro St., Campinas, SP 13083-970, Brazil

3. Faculty of Pharmaceutical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 580 Cidade Universitária, São Paulo, SP 05508-900, Brazil

4. Department of Physiology, University of Sao Paulo, Rua do Matão 101, Travessa 14, São Paulo, SP 05508-090, Brazil

5. Faculty of Pharmaceutical Sciences, State University of Campinas, Rua Oswaldo Cruz, 2° Andar, Bloco F3, Cidade Universitária, Campinas, SP 13083-859, Brazil

Funder

Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico

Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo

Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior

Instituto Serrapilheira

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference64 articles.

1. World Health Organization (WHO). World Malaria Report 2016. http://www.who.int/malaria/publications/world-malaria-report-2016/report/en/ (accessed September 24, 2016).

2. Antimalarial drug discovery – the path towards eradication

3. Antimalarial drug discovery — approaches and progress towards new medicines

4. Antimalarial Drug Discovery: From Quinine to the Dream of Eradication

5. Malaria

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