Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite-Reference-Cited by-同舟云学术

Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite

Published:2018-05-21 Issue:13 Volume:61 Page:5664-5678
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Das Pronay¹²,Babbar Palak³,Malhotra Nipun³,Sharma Manmohan³,Jachak Goraknath R.¹²,Gonnade Rajesh G.²⁴^ORCID,Shanmugam Dhanasekaran²⁵,Harlos Karl⁶,Yogavel Manickam³,Sharma Amit³,Reddy D. Srinivasa¹²^ORCID

Affiliation:

1. Organic Chemistry Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411008, India

2. Academy of Scientific and Innovative Research (AcSIR), New Delhi 110025, India

3. Molecular Medicine Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi 110067, India

4. Center for Material Characterization, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411008, India

5. Biochemical Sciences Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411008, India

6. Division of Structural Biology, Wellcome Trust Centre for Human Genetics, The Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, U.K.

Funder

Council of Scientific and Industrial Research

University Grants Commission

Department of Science and Technology, Ministry of Science and Technology

Wellcome Trust

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00565

Reference31 articles.