Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5-Reference-Cited by-同舟云学术

Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5

Published:2019-01-09 Issue:3 Volume:62 Page:1246-1273
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Graziani Davide¹^ORCID,Caligari Silvia¹,Callegari Elisa¹,De Toma Carlo¹,Longhi Matteo¹,Frigerio Fabio¹,Dilernia Roberto¹,Menegon Sergio¹,Pinzi Luca²,Pirona Lorenza¹,Tazzari Valerio¹,Valsecchi Anna Elisa¹,Vistoli Giulio³^ORCID,Rastelli Giulio²^ORCID,Riva Carlo¹

Affiliation:

1. Drug Discovery Department, Recordati S.p.A., Via M. Civitali 1, 20148 Milan, Italy

2. Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125 Modena, Italy

3. Department of Pharmaceutical Sciences, Università degli Studi di Milano, Via Mangiagalli 25, 20133 Milan, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01226

Reference68 articles.

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