Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors-Reference-Cited by-同舟云学术

Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors

Published:2018-06-25 Issue:14 Volume:61 Page:6034-6055
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sainas Stefano^ORCID,Pippione Agnese C.^ORCID,Lupino Elisa^ORCID,Giorgis Marta^ORCID,Circosta Paola¹²^ORCID,Gaidano Valentina³⁴^ORCID,Goyal Parveen⁵^ORCID,Bonanni Davide^ORCID,Rolando Barbara^ORCID,Cignetti Alessandro³⁴^ORCID,Ducime Alex^ORCID,Andersson Mikael⁵^ORCID,Järvå Michael⁶^ORCID,Friemann Rosmarie⁵^ORCID,Piccinini Marco^ORCID,Ramondetti Cristina^ORCID,Buccinnà Barbara^ORCID,Al-Karadaghi Salam⁷^ORCID,Boschi Donatella^ORCID,Saglio Giuseppe³⁴^ORCID,Lolli Marco L.^ORCID

Affiliation:

1. Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin 10126, Italy

2. Molecular Biotechnology Center, Turin 10126, Italy

3. Department of Clinical and Biological Sciences, University of Turin, Turin 10043, Italy

4. Mauriziano Hospital S.C.D.U. Hematology, Turin 10128, Italy

5. Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg SE 405, Sweden

6. Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia

7. Department of Biochemistry and Structural Biology, Lund University, Lund 221 00, Sweden

Funder

Università degli Studi di Torino

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00373

Reference65 articles.

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5. Leflunomide: an immunomodulatory drug for the treatment of rheumatoid arthritis and other autoimmune diseases

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