MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria-Reference-Cited by-同舟云学术

MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria

Published:2018-09-07 Issue:19 Volume:61 Page:8847-8858
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Xu¹,Edwards Rachel L.²^ORCID,Ball Haley³,Johnson Claire³,Haymond Amanda³,Girma Misgina³,Manikkam Michelle⁴,Brothers Robert C.¹,McKay Kyle T.¹,Arnett Stacy D.⁵,Osbourn Damon M.⁶,Alvarez Sophie⁷^ORCID,Boshoff Helena I.⁴^ORCID,Meyers Marvin J.⁵⁸^ORCID,Couch Robin D.³,Odom John Audrey R.²^ORCID,Dowd Cynthia S.¹^ORCID

Affiliation:

1. Department of Chemistry, George Washington University, Washington D.C. 20052, United States

2. Department of Pediatrics, Washington University School of Medicine, Washington University, St. Louis, Missouri 63110, United States

3. Department of Chemistry and Biochemistry, George Mason University, Manassas, Virginia 20110, United States

4. Tuberculosis Research Section, LCIM, NIAID/NIH, Bethesda, Maryland 20892, United States

5. Department of Pharmacology and Physiology, Saint Louis University, St. Louis, Missouri 63104, United States

6. Department of Molecular Microbiology and Immunology, Saint Louis University, St. Louis, Missouri 63104, United States

7. Proteomics & Metabolomics Facility, Center for Biotechnology, Department of Agronomy and Horticulture, University of Nebraska—Lincoln, Lincoln, Nebraska 68588, United States

8. Department of Chemistry, Saint Louis University, St. Louis, Missouri 63103, United States

Funder

George Washington University

National Institute of Allergy and Infectious Diseases

Department of Chemistry, George Washington University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01026

Reference48 articles.