Easy-To-Synthesize Spirocyclic Compounds Possess Remarkable in Vivo Activity against Mycobacterium tuberculosis-Reference-Cited by-同舟云学术

Easy-To-Synthesize Spirocyclic Compounds Possess Remarkable in Vivo Activity against Mycobacterium tuberculosis

Published:2018-11-20 Issue:24 Volume:61 Page:11327-11340
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Guardia Ana¹,Baiget Jessica²,Cacho Mónica¹,Pérez Arancha¹,Ortega-Guerra Montserrat¹,Nxumalo Winston¹,Khanye Setshaba D.¹,Rullas Joaquín¹,Ortega Fátima¹,Jiménez Elena¹,Pérez-Herrán Esther¹,Fraile-Gabaldón María Teresa¹,Esquivias Jorge¹,Fernández Raquel¹,Porras-De Francisco Esther¹,Encinas Lourdes¹,Alonso Marta¹,Giordano Ilaria¹,Rivero Cristina¹,Miguel-Siles Juan¹,Osende Javier G.²,Badiola Katrina A.²,Rutledge Peter J.²^ORCID,Todd Matthew H.²³^ORCID,Remuiñán Modesto¹,Alemparte Carlos¹

Affiliation:

1. GlaxoSmithKline, Tres Cantos Medicines Development Campus, Severo Ochoa 2, 28760 Tres Cantos, Madrid, Spain

2. School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia

3. School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, U.K.

Funder

GlaxoSmithKline

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01533

Reference33 articles.

1. aWHO Global Tuberculosis Report 2018. http://www.who.int/tb/publications/global_report/en/ (accessed Nov 14, 2018).

2. Global Tuberculosis Control: Toward the 2015 Targets and Beyond

3. Advances in the development of new tuberculosis drugs and treatment regimens

4. Working Group on New TB Drugs, http://www.newtbdrugs.org/ (accessed Nov 14, 2018).

5. Multidrug-resistant and extensively drug-resistant tuberculosis: a review of current concepts and future challenges

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