Optimization of Vinyl Sulfone Derivatives as Potent Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activators for Parkinson’s Disease Therapy-Reference-Cited by-同舟云学术

Optimization of Vinyl Sulfone Derivatives as Potent Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activators for Parkinson’s Disease Therapy

Published:2018-12-12 Issue:2 Volume:62 Page:811-830
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Choi Ji Won¹,Kim Siwon¹²,Park Jong-Hyun¹,Kim Hyeon Jeong¹³,Shin Su Jeong¹,Kim Jin Woo¹,Woo Seo Yeon¹,Lee Changho⁴,Han Sang Moon⁵,Lee Jaeick⁵^ORCID,Pae Ae Nim¹²⁶,Han Gyoonhee³,Park Ki Duk¹²⁶^ORCID

Affiliation:

1. Convergence Research Center for Diagnosis, Treatment & Care System of Dementia, Korea Institute of Science & Technology (KIST), Seoul 02792, Republic of Korea

2. Division of Bio-Med Science & Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Republic of Korea

3. Department of Biotechnology, Yonsei University, Seoul 03722, Republic of Korea

4. Division of Functional Food Research, Korea Food Research Institute, Wanju-gun, Jeollabuk-do 55365, Republic of Korea

5. Doping Control Center, KIST, Seoul 02792, Republic of Korea

6. KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul 02447, Republic of Korea

Funder

Korea Food Research Institute

National Research Council of Science and Technology

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01527

Reference32 articles.

1. Ageing and Parkinson's disease: Why is advancing age the biggest risk factor?

2. Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

3. Neuroprotective and Therapeutic Strategies against Parkinson’s Disease: Recent Perspectives

4. Pathogenesis-Targeted, Disease-Modifying Therapies in Parkinson Disease

5. Parkinson's Disease Therapeutics: New Developments and Challenges Since the Introduction of Levodopa

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