Design and Evaluation of Potent EGFR Inhibitors through the Incorporation of Macrocyclic Polyamine Moieties into the 4-Anilinoquinazoline Scaffold
Author:
Affiliation:
1. State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China
2. State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100871, P. R. China
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01612
Reference39 articles.
1. Untangling the ErbB signalling network
2. ERBB receptors and cancer: the complexity of targeted inhibitors
3. EGFR Antagonists in Cancer Treatment
4. Anaplastic lymphoma kinase (ALK): Structure, oncogenic activation, and pharmacological inhibition
5. Status of Epidermal Growth Factor Receptor Antagonists in the Biology and Treatment of Cancer
Cited by 27 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Unraveling the future: Innovative design strategies and emerging challenges in HER2-targeted tyrosine kinase inhibitors for cancer therapy;European Journal of Medicinal Chemistry;2024-10
2. Design and activity evaluation of new EGFR tyrosine kinase inhibitors containing cyclic polyamines;Bioorganic & Medicinal Chemistry Letters;2024-09
3. Discovery of a Potent Dual Son of Sevenless 1 (SOS1) and Epidermal Growth Factor Receptor (EGFR) Inhibitor for the Treatment of Prostate Cancer;Journal of Medicinal Chemistry;2024-04-17
4. Continuous Flow Synthesis of a Key Intermediate Common to Gefitinib and Larotinib;Organic Process Research & Development;2024-02-20
5. Design and Activity Evaluation of Small Molecule Tyrosine Kinase Inhibitors Bearing Cyclic Polyamines;2024
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3