(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation-Reference-Cited by-同舟云学术

(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation

Published:2018-02-16 Issue:5 Volume:61 Page:2124-2130
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Brogi Simone¹,Brindisi Margherita¹,Butini Stefania¹^ORCID,Kshirsagar Giridhar U.¹,Maramai Samuele¹,Chemi Giulia¹,Gemma Sandra¹^ORCID,Campiani Giuseppe¹,Novellino Ettore²^ORCID,Fiorenzani Paolo³,Pinassi Jessica³,Aloisi Anna Maria³,Gynther Mikko⁴,Venskutonytė Raminta⁵,Han Liwei⁵,Frydenvang Karla⁵,Kastrup Jette Sandholm⁵^ORCID,Pickering Darryl S.⁵^ORCID

Affiliation:

1. Department of Biotechnology, Chemistry and Pharmacy, (DoE 2018-2022) NatSynDrugs, University of Siena, Via A. Moro 2, 53100 Siena, Italy

2. Department of Pharmacy, University of Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy

3. Department of Medicine, Surgery and Neuroscience, University of Siena, Viale M. Bracci 16, 53100 Siena, Italy

4. School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, 70211 Kuopio, Finland

5. Department of Drug Design and Pharmacology, University of Copenhagen, Jagtvej 162, DK-2100 Copenhagen, Denmark

Funder

Lundbeckfonden

Danscatt

GluTarget

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00099

Reference25 articles.

1. Glutamate Receptor Ion Channels: Structure, Regulation, and Function

2. GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses

3. X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

4. Kainate receptors and synaptic transmission

5. Kainate receptors: Pharmacology, function and therapeutic potential

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Lithocholic acid derivatives as potent modulators of the nuclear receptor RORγt;RSC Advances;2024

2. Small‐molecule positive allosteric modulation of homomeric kainate receptors GluK1‐3: development of screening assays and insight into GluK3 structure;The FEBS Journal;2023-12-25

3. Small molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: Development of screening assays and insight into GluK3 structure;2023-11-02

4. Comparative study of manganese oxides with different oxidation states for catalytic carbonylation of n-butylamine by CO2;Journal of CO2 Utilization;2023-02

5. Kainate Receptor Antagonists: Recent Advances and Therapeutic Perspective;International Journal of Molecular Sciences;2023-01-18