Development of Macrocyclic Peptidomimetics Containing Constrained α,α-Dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors

Author:

Merlino Francesco1ORCID,Zhou Yang2,Cai Minying2ORCID,Carotenuto Alfonso1ORCID,Yousif Ali M.1,Brancaccio Diego1,Di Maro Salvatore3ORCID,Zappavigna Silvia4,Limatola Antonio5,Novellino Ettore1ORCID,Grieco Paolo1ORCID,Hruby Victor J.2

Affiliation:

1. Department of Pharmacy, University of Naples “Federico II”, Via D. Montesano 49, 80131 Naples, Italy

2. Department of Chemistry and Biochemistry, University of Arizona, 1306 E. University Boulevard, Tucson, Arizona 85721, United States

3. DiSTABiF, University of Campania “Luigi Vanvitelli”, Via Vivaldi 43, 81100 Caserta, Italy

4. Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, Via Costantinopoli 16, 80138 Naples, Italy

5. Department of Biology, Stanford University, Stanford, California 94305, United States

Funder

Universit? degli Studi di Napoli Federico II

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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