Tumor-Targeted Delivery of 6-Diazo-5-oxo-l-norleucine (DON) Using Substituted Acetylated Lysine Prodrugs-Reference-Cited by-同舟云学术

Tumor-Targeted Delivery of 6-Diazo-5-oxo-l-norleucine (DON) Using Substituted Acetylated Lysine Prodrugs

Published:2019-03-20 Issue:7 Volume:62 Page:3524-3538
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tenora Lukáš¹,Alt Jesse,Dash Ranjeet P.,Gadiano Alexandra J.,Novotná Kateřina¹,Veeravalli Vijayabhaskar,Lam Jenny,Kirkpatrick Quinn R.,Lemberg Kathryn M.,Majer Pavel¹,Rais Rana^ORCID,Slusher Barbara S.^ORCID

Affiliation:

1. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic v.v.i., Prague 166 10, Czech Republic

Funder

Ministerstvo ?kolstv?, Ml?de?e a Telov?chovy

National Cancer Institute

National Institute of Neurological Disorders and Stroke

Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b02009

Reference46 articles.

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4. Metabolism and action of amino acid analog anti-cancer agents

5. Structural Basis for the Active Site Inhibition Mechanism of Human Kidney-Type Glutaminase (KGA)

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