Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi

Author:

Martín-Escolano Rubén1,Moreno-Viguri Elsa2ORCID,Santivañez-Veliz Mery2,Martin-Montes Alvaro1,Medina-Carmona Encarnación3,Paucar Rocío2,Marín Clotilde1ORCID,Azqueta Amaya4,Cirauqui Nuria5,Pey Angel L.3,Pérez-Silanes Silvia2ORCID,Sánchez-Moreno Manuel1

Affiliation:

1. Departament of Parasitology, Instituto de Investigación Biosanitaria (ibs.Granada), Hospitales Universitarios De Granada/University of Granada, Severo Ochoa s/n, E-18071 Granada, Spain

2. Universidad de Navarra, Department of Organic and Pharmaceutical Chemistry, Instituto de Salud Tropical, Pamplona 31008, Spain

3. Department of Physical Chemistry, Faculty of Sciences, University of Granada, Av. Fuentenueva s/n, 18071 Granada, Spain

4. Universidad de Navarra, Department of Pharmacology and Toxicology, Pamplona 31008, Spain

5. Department of Pharmaceutical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro 21949-900, Brazil

Funder

Ministerio de Ciencia e Innovaci?n

Ministerio de Econom?a y Competitividad

Fundaci?n Caja Navarra

Ministerio de Educaci?n, Cultura y Deporte

Universidad de Navarra

Artai

Fundaci?n Roviralta

Junta de Andalucia

PROFAND

Obra Social la CAIXA

Ubesol

ACUNSA

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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