Structure-Based Drug Design of Potent Pyrazole Derivatives against Rhinovirus Replication

Author:

Da Costa Laurène1ORCID,Scheers Els2,Coluccia Antonio3ORCID,Casulli Adriano4,Roche Manon1,Di Giorgio Carole5,Neyts Johan2,Terme Thierry1,Cirilli Roberto6ORCID,La Regina Giuseppe3ORCID,Silvestri Romano3ORCID,Mirabelli Carmen2,Vanelle Patrice1

Affiliation:

1. Aix-Marseille Univ, Institut de Chimie Radicalaire, Laboratoire de Pharmacochimie Radicalaire, UMR 7273 CNRS, 27 Boulevard Jean Moulin, 13385 Marseille, Cedex 05, France

2. KU Leuven−University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000 Leuven, Belgium

3. Department of Drug Chemistry and Technologies, Sapienza University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Piazzale Aldo Moro 5, I-00185 Rome, Italy

4. WHO Collaborating Centre for the Epidemiology, Detection and Control of Cystic and Alveolar Echinococcosis, European Reference Laboratory for Parasites, Department of Infectious Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, I-00161 Rome, Italy

5. Aix-Marseille Univ, CNRS, IRD, Avignon Université, IMBE UMR 7263, Laboratoire de Mutagénèse Environnementale, 27 Boulevard Jean Moulin, 13385 Marseille, Cedex 05, France

6. Centro nazionale per il controllo e la valutazione dei farmaci, Istituto Superiore di Sanità, Viale Regina Elena 299, I-00161 Rome, Italy

Funder

Aix-Marseille Universit?

Centre National de la Recherche Scientifique

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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