Activation of Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonates Prodrugs by CYP1A1 as New Antimitotics Targeting Breast Cancer Cells

Author:

Fortin Sébastien12ORCID,Charest-Morin Xavier1,Turcotte Vanessa1,Lauvaux Coraline3,Lacroix Jacques1,Côté Marie-France1,Gobeil Stéphane34,C.-Gaudreault René14

Affiliation:

1. CHU de Québec Research Centre, Oncology Division, Hôpital Saint-François d’Assise, 10 rue de l’Espinay, Quebec City, Quebec, Canada G1L 3L5

2. Faculty of Pharmacy, Université Laval, Quebec City, Quebec, Canada G1V 0A6

3. CHU de Québec Research Centre, Endocrinology and Nephrology Division, CHUL, 2705 Boulevard Laurier, Quebec City, Quebec, Canada G1V 4G2

4. Department of Molecular Medicine, Faculty of Medicine, Université Laval, Quebec City, Quebec, Canada G1V 0A6

Funder

Canadian Institutes of Health Research

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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