Utilization of an Active Site Mutant Receptor for the Identification of Potent and Selective Atypical 5-HT2C Receptor Agonists-Reference-Cited by-同舟云学术

Utilization of an Active Site Mutant Receptor for the Identification of Potent and Selective Atypical 5-HT2C Receptor Agonists

Published:2017-07-07 Issue:14 Volume:60 Page:6166-6190
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Carpenter Joseph¹^ORCID,Wang Ying¹,Wu Gang¹,Feng Jianxin¹,Ye Xiang-Yang¹^ORCID,Morales Christian L.¹,Broekema Matthias¹,Rossi Karen A.¹,Miller Keith J.¹,Murphy Brian J.¹,Wu Ginger¹,Malmstrom Sarah E.¹,Azzara Anthony V.¹,Sher Philip M.¹,Fevig John M.¹,Alt Andrew¹,Bertekap Robert L.¹,Cullen Mary Jane¹,Harper Timothy M.¹,Foster Kimberly¹,Luk Emily¹,Xiang Qian¹,Grubb Mary F.¹,Robl Jeffrey A.¹,Wacker Dean A.¹

Affiliation:

1. Departments of Discovery Chemistry, Discovery Biology, Lead Evaluation, Computer-Assisted Drug Design, Discovery Toxicology, and Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Pharmaceutical Research Institute, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00385

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