Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer-Reference-Cited by-同舟云学术

Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer

Published:2017-12-07 Issue:24 Volume:60 Page:9990-10012
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ouyang Liang¹,Zhang Lan¹,Liu Jie¹,Fu Leilei¹,Yao Dahong¹,Zhao Yuqian¹,Zhang Shouyue¹,Wang Guan¹,He Gu¹^ORCID,Liu Bo¹^ORCID

Affiliation:

1. State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00275

Reference56 articles.

1. BET domain co-regulators in obesity, inflammation and cancer

2. Place your BETs: the therapeutic potential of bromodomains