Structural Optimizations of Thieno[3,2-b]pyrrole Derivatives for the Development of Metabolically Stable Inhibitors of Chikungunya Virus-Reference-Cited by-同舟云学术

Structural Optimizations of Thieno[3,2-b]pyrrole Derivatives for the Development of Metabolically Stable Inhibitors of Chikungunya Virus

Published:2017-04-04 Issue:7 Volume:60 Page:3165-3186
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ching Kuan-Chieh¹²,Tran Thi Ngoc Quy²,Amrun Siti Naqiah³,Kam Yiu-Wing³,Ng Lisa F. P.³⁴,Chai Christina L. L.¹²⁵^ORCID

Affiliation:

1. NUS Graduate School for Integrative Sciences and Engineering, Centre for Life Sciences, No. 05-01, 28 Medical Drive, 117456, Singapore

2. Department of Pharmacy, Faculty of Science, National University of Singapore, Block S4A, Level 3, 18 Science Drive 4, 117543, Singapore

3. Singapore Immunology Network, A*STAR, 8A Biomedical Grove, Immunos Building, No. 04-06, 138648, Singapore

4. Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Block MD6, Centre for Translational Medicine, 14 Medical Drive, No. 14-01T, 117599, Singapore

5. Institute of Chemical and Engineering Sciences, A*STAR, 8 Biomedical Grove, Neuros Building, No. 07-01/02/03, 138665, Singapore

Funder

Agency for Science, Technology and Research

Ministry of Education - Singapore

National University of Singapore

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00180

Reference44 articles.

1. Chikungunya: a bending reality

2. Chikungunya virus pathogenesis: From bedside to bench

3. Updates on Chikungunya Epidemiology, Clinical Disease, and Diagnostics

4. Biology and pathogenesis of chikungunya virus

5. Chikungunya in Southeast Asia: understanding the emergence and finding solutions

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