Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a “Bio-Oxidizable” Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation-Reference-Cited by-同舟云学术

Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a “Bio-Oxidizable” Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation

Published:2017-06-29 Issue:13 Volume:60 Page:5909-5926
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Peauger Ludovic¹,Azzouz Rabah¹,Gembus Vincent¹,Ţînţaş Mihaela-Liliana²,Sopková-de Oliveira Santos Jana³,Bohn Pierre⁴,Papamicaël Cyril²,Levacher Vincent²^ORCID

Affiliation:

1. VFP Therapies, 15 rue François Couperin, 76000 Rouen, France

2. Normandie Université, COBRA, UMR 6014 et FR 3038, Univ Rouen, INSA Rouen, CNRS, IRCOF, 1 rue Tesnière, 76821 Mont Saint Aignan Cedex, France

3. Centre d’Etudes et de Recherche sur le Médicament de Normandie, Université de Caen, Boulevard Becquerel, 14032 Caen Cedex, France

4. Department of Nuclear Medicine, Henri Becquerel Cancer Center and Rouen University Hospital and QuantIF LITIS (Equipe d’Accueil (EA) 4108-Federation Recherche (FR) National Center for Scientific Research (CNRS) 3638), Faculty of Medicine, University of Rouen, Rouen 76821, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00702

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