Antitubercular Bis-Substituted Cyclam Derivatives: Structure–Activity Relationships and in Vivo Studies

Author:

Spain Malcolm1,Wong Joseph K.-H.1,Nagalingam Gayathri2,Batten James M.1,Hortle Elinor3,Oehlers Stefan H.4,Jiang Xiao Fan1,Murage Hasini E.1,Orford Jack T.1,Crisologo Patrick1,Triccas James A.2,Rutledge Peter J.1ORCID,Todd Matthew H.1ORCID

Affiliation:

1. School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia

2. Microbial Immunity and Pathogenesis Group, Department of Infectious Diseases and Immunology, Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia

3. Tuberculosis Research Program, Centenary Institute, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, NSW 2050, Australia

4. Central Clinical School, Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia

Funder

National Health and Medical Research Council

Sydnovate Fund, University of Sydney

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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