Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 Agonists-Reference-Cited by-同舟云学术

Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 Agonists

Published:2018-01-27 Issue:3 Volume:61 Page:681-694
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shi Jun¹^ORCID,Gu Zhengxiang¹,Jurica Elizabeth Anne¹^ORCID,Wu Ximao¹,Haque Lauren E.¹,Williams Kristin N.¹,Hernandez Andres S.¹,Hong Zhenqiu¹,Gao Qi¹,Dabros Marta¹,Davulcu Akin H.¹,Mathur Arvind¹,Rampulla Richard A.¹,Gupta Arun Kumar¹,Jayaram Ramya¹,Apedo Atsu¹,Moore Douglas B.¹,Liu Heng¹,Kunselman Lori K.¹,Brady Edward J.¹,Wilkes Jason J.¹,Zinker Bradley A.¹,Cai Hong¹,Shu Yue-Zhong¹,Sun Qin¹,Dierks Elizabeth A.¹,Foster Kimberly A.¹,Xu Carrie¹,Wang Tao¹,Panemangalore Reshma¹,Cvijic Mary Ellen¹,Xie Chunshan¹,Cao Gary G.¹,Zhou Min¹,Krupinski John¹,Whaley Jean M.¹,Robl Jeffrey A.¹,Ewing William R.¹,Ellsworth Bruce Alan¹

Affiliation:

1. Research and Development, Bristol-Myers Squibb Co., P.O. Box 4000, Princeton, New Jersey 08540-4000, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00982

Reference23 articles.

1. The Ideal Diabetes Therapy: What Will It Look Like? How Close Are We?

2. World health organization diabetes fact sheet 2013,http://www.who.int/mediacentre/factsheets/fs312/en/(accessed on Feb 29, 2016).

3. International diabetes federation.Diabetes Atlas, 8th ed., 2017,http://www.diabetesatlas.org/resources/2017-atlas.html(accessed Dec 11, 2017).

4. Standards of Medical Care in Diabetes--2015: Summary of Revisions

5. The incretin system and its role in type 2 diabetes mellitus

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A One-Pot Two-Step Three-Component Stereoselective Mechanosynthesis of Ester-Functionalized Multisubstituted Δ²-Pyrazolines and Their Application in the Detection of Fluoride Ions;ACS Sustainable Chemistry & Engineering;2024-09-02

2. Evolution of the Synthetic Process to an Advanced GPR40 Agonist;Organic Process Research & Development;2024-01-02

3. Synthetic GPR40/FFAR1 agonists: An exhaustive survey on the most recent chemical classes and their structure-activity relationships;European Journal of Medicinal Chemistry;2024-01

4. 4-Trifluoromethoxy proline: synthesis of stereoisomers and lipophilicity study;Organic & Biomolecular Chemistry;2024

5. A Concise, Stereoselective and Scalable Synthesis of Optically Pure (3r,4r)-1-Benzyl- and (3r,4r)-1-Boc-3-Methyl-4-Aminopiperidines;2024