Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors

Author:

Aghazadeh Tabrizi Mojgan1,Baraldi Pier Giovanni1,Baraldi Stefania1,Ruggiero Emanuela1,De Stefano Lucia23,Rizzolio Flavio34,Di Cesare Mannelli Lorenzo5,Ghelardini Carla5,Chicca Andrea6,Lapillo Margherita76,Gertsch Jürg6ORCID,Manera Clementina7,Macchia Marco7,Martinelli Adriano7,Granchi Carlotta7,Minutolo Filippo7ORCID,Tuccinardi Tiziano78ORCID

Affiliation:

1. Department of Chemical and Pharmaceutical Sciences, University of Ferrara, 44121 Ferrara, Italy

2. Graduate School in Chemistry, University of Trieste, 34127 Trieste, Italy

3. Division of Experimental and Clinical Pharmacology, Department of Molecular Biology and Translational Research, National Cancer Institute and Center for Molecular Biomedicine, 33081 Aviano, Pordenone, Italy

4. Department of Molecular Science and Nanosystems, Ca’ Foscari Università di Venezia, 30172 Venezia-Mestre, Italy

5. Department of Neuroscience, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Firenze, 50139 Firenze, Italy

6. Institute of Biochemistry and Molecular Medicine, NCCR TransCure, University of Bern, CH-3012 Bern, Switzerland

7. Department of Pharmacy, University of Pisa, 56126 Pisa, Italy

8. Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania 19122, United States

Funder

Universit? di Pisa

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3