Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656)-Reference-Cited by-同舟云学术

Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656)

Published:2017-09-27 Issue:19 Volume:60 Page:8011-8026
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Xianfeng¹,Hernandez Vincent¹,Rock Fernando L.¹,Choi Wai¹,Mak Yvonne S. L.¹,Mohan Manisha¹,Mao Weimin¹,Zhou Yasheen¹,Easom Eric E.¹,Plattner Jacob J.¹,Zou Wuxin²,Pérez-Herrán Esther³,Giordano Ilaria³,Mendoza-Losana Alfonso³,Alemparte Carlos³,Rullas Joaquín³,Angulo-Barturen Iñigo³,Crouch Sabrinia³,Ortega Fátima³,Barros David³^ORCID,Alley M. R. K.¹

Affiliation:

1. Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, California 94303, United States

2. BioDuro LLC, Building E, No. 29, Life Science Park Road, Beijing 102206, P. R. China

3. GlaxoSmithKline, Tres Cantos Medicines Development Campus, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00631

Reference31 articles.

1. WHO. Global Tuberculosis Report 2016.World Health Organization:Geneva, 2016; http://www.who.int/tb/publications/global_report/en/(accessed November 22, 2016).

2. Review: Multidrug-resistant tuberculosis: public health challenges

3. ERS/WHO Tuberculosis Consilium assistance with extensively drug-resistant tuberculosis management in a child: case study of compassionate delamanid use

4. Totally Drug-Resistant Tuberculosis in India

5. New agents for the treatment of drug-resistant Mycobacterium tuberculosis

Cited by 127 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent advances and challenges of revolutionizing drug-resistant tuberculosis treatment;European Journal of Medicinal Chemistry;2024-11

2. A Review of Antibacterial Candidates with New Modes of Action;ACS Infectious Diseases;2024-07-17

3. Small Molecule Targeting PPM1A Activates Autophagy for Mycobacterium tuberculosis Host-Directed Therapy;Journal of Medicinal Chemistry;2024-07-03

4. Insights into the Effects of Ligand Binding on Leucyl-tRNA Synthetase Inhibitors for Tuberculosis: In Silico Analysis and Isothermal Titration Calorimetry Validation;Biomolecules;2024-06-16

5. Direct inhibitors of InhA with efficacy similar or superior to isoniazid in novel drug regimens for tuberculosis;2024-03-14