Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c-MYC Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex-Reference-Cited by-同舟云学术

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Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c-MYC Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex

Published:2018-02-23 Issue:6 Volume:61 Page:2447-2459
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hu Ming-Hao¹²,Wang Yu-Qing¹,Yu Ze-Yi¹,Hu Lu-Ni¹,Ou Tian-Miao¹^ORCID,Chen Shuo-Bin¹,Huang Zhi-Shu¹^ORCID,Tan Jia-Heng¹^ORCID

Affiliation:

1. School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China

2. School of Pharmaceutical Sciences, Shenzhen University Health Science Center, Shenzhen 518060, China

Funder

State Administration of Foreign Experts Affairs

Ministry of Education of the People's Republic of China

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Guangdong Provincial Key Laboratory of Construction Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01697

Reference46 articles.

1. Quadruplex DNA: sequence, topology and structure

2. Structural insights into G-quadruplexes: towards new anticancer drugs

3. High-throughput sequencing of DNA G-quadruplex structures in the human genome

4. G-quadruplex structures mark human regulatory chromatin

5. Quantitative visualization of DNA G-quadruplex structures in human cells

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4. Spotlight on G-Quadruplexes: From Structure and Modulation to Physiological and Pathological Roles;International Journal of Molecular Sciences;2024-03-09

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