Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism-Reference-Cited by-同舟云学术

Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism

Published:2017-10-16 Issue:20 Volume:60 Page:8631-8646
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Naik Ravi¹,Ban Hyun Seung²³^ORCID,Jang Kyusic¹,Kim Inhyub⁴⁵,Xu Xuezhen¹,Harmalkar Dipesh¹,Shin Seong-Ah⁴,Kim Minkyoung¹,Kim Bo-Kyung⁴,Park Jaehyung¹,Ku Bonsu⁶,Oh Sujin⁷,Won Misun⁴⁵,Lee Kyeong¹^ORCID

Affiliation:

1. College of Pharmacy, Dongguk University, Goyang 10326, Korea

2. Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea

3. Biomolecular Science, University of Science and Technology, Daejeon 34113, Korea

4. Personalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea

5. Functional Genomics, University of Science and Technology, Daejeon 34113, Korea

6. Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea

7. New Drug Development Center, Asan Medical Center, Seoul 05505, Korea

Funder

Ministry of Health and Welfare

Korea Research Council of Fundamental Science and Technology

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01231

Reference34 articles.

1. Regulation of cancer cell metabolism

2. Control of the Removal of Reducing Equivalents from the Cytosol in Perfused Rat Liver

3. Malate-Aspartate Shuttle, Cytoplasmic NADH Redox Potential, and Energetics in Vascular Smooth Muscle

4. Targeting aspartate aminotransferase in breast cancer

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Phillyrin and its metabolites exert antipyretic effects by targeting the NAD+ binding domain of GAPDH, MDH2 and IDH2;Phytomedicine;2024-11

2. Physiology of malate dehydrogenase and how dysregulation leads to disease;Essays in Biochemistry;2024-07-04

3. Malate dehydrogenase as a multi-purpose target for drug discovery;Essays in Biochemistry;2024-05-31

4. Insights into the regulation of malate dehydrogenase: inhibitors, activators, and allosteric modulation by small molecules;Essays in Biochemistry;2024-05-30

5. Colorectal Cancer in Correlation With Clinicopathological Variables: The Effects of Hypoxia-Inducible Factor-1 Alfa or the InterLeukin-33 and Vascular Endothelial Growth Factor?;Cureus;2024-01-04