Highly Selective and Potent α4β2 nAChR Antagonist Inhibits Nicotine Self-Administration and Reinstatement in Rats-Reference-Cited by-同舟云学术

Highly Selective and Potent α4β2 nAChR Antagonist Inhibits Nicotine Self-Administration and Reinstatement in Rats

Published:2017-12-13 Issue:24 Volume:60 Page:10092-10104
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wu Jinhua¹²^ORCID,Cippitelli Andrea¹,Zhang Yaohong¹³⁴,Debevec Ginamarie¹,Schoch Jennifer¹,Ozawa Akihiko¹,Yu Yongping¹³,Liu Huan³,Chen Wenteng³,Houghten Richard A.¹²,Welmaker Gregory S.¹²,Giulianotti Marc A.¹²,Toll Lawrence¹²

Affiliation:

1. Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway, Port St. Lucie, Florida 34987, United States

2. Assuage Pharmaceuticals, Inc, 11350 SW Village Parkway, Port St. Lucie, Florida 34987, United States

3. Institute of Materia Medica, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, P. R. China

4. School of Chemistry and Chemical Engineering, Zhejiang Key Laboratory of Alternative Technologies for Fine Chemicals Process, Shaoxing University, Shaoxing 312000, Zhejiang, P. R. China

Funder

National Institute on Drug Abuse

Department of Economic Opportunity, State of Florida

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01250

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4. Efficacy of Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking CessationA Randomized Controlled Trial

5. Multimodal techniques for smoking cessation: a review of their efficacy and utilisation and clinical practice guidelines

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