Discovery of an Orally Bioavailable, Brain-Penetrating, in Vivo Active Phosphodiesterase 2A Inhibitor Lead Series for the Treatment of Cognitive Disorders-Reference-Cited by-同舟云学术

Discovery of an Orally Bioavailable, Brain-Penetrating, in Vivo Active Phosphodiesterase 2A Inhibitor Lead Series for the Treatment of Cognitive Disorders

Published:2017-09-11 Issue:18 Volume:60 Page:7658-7676
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mikami Satoshi¹^ORCID,Sasaki Shigekazu¹,Asano Yasutomi¹,Ujikawa Osamu¹,Fukumoto Shoji¹,Nakashima Kosuke¹,Oki Hideyuki¹,Kamiguchi Naomi¹,Imada Haruka¹,Iwashita Hiroki¹,Taniguchi Takahiko¹

Affiliation:

1. Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00709

Reference51 articles.

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4. Advances in targeting cyclic nucleotide phosphodiesterases

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