Synthesis, Pharmacology, and Molecular Docking Studies on 6-Desoxo-N-methylmorphinans as Potent μ-Opioid Receptor Agonists
Author:
Affiliation:
1. Department of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria
Funder
Austrian Science Fund
Tyrolean Research Fund
Swarovski Kristallwelten Wattens
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01363
Reference44 articles.
1. Morphine: New aspects in the study of an ancient compound
2. Mu Opioids and Their Receptors: Evolution of a Concept
3. The µ Opioid Receptor and Ligands Acting at the µ Opioid Receptor, as Therapeutics and Potential Therapeutics
4. Re-energizing the Development of Pain Therapeutics in Light of the Opioid Epidemic
5. Time for nonaddictive relief of pain
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