Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile-Reference-Cited by-同舟云学术

Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile

Published:2018-02-09 Issue:5 Volume:61 Page:1785-1799
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ripa Lena¹^ORCID,Edman Karl²,Dearman Matthew¹,Edenro Goran¹,Hendrickx Ramon¹,Ullah Victoria¹,Chang Hui-Fang¹,Lepistö Matti¹,Chapman Dave¹,Geschwindner Stefan²^ORCID,Wissler Lisa²,Svanberg Petter¹,Lawitz Karolina³,Malmberg Jesper¹,Nikitidis Antonios¹,Olsson Roine I.¹,Bird James¹,Llinas Antoni¹^ORCID,Hegelund-Myrbäck Tove¹,Berger Markus⁴^ORCID,Thorne Philip⁵,Harrison Richard⁵,Köhler Christian²,Drmota Tomas¹

Affiliation:

1. Respiratory, Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca Gothenburg, Pepparedsleden 1, Mölndal 43183, Sweden

2. Discovery Sciences, IMED Biotech Unit, AstraZeneca Gothenburg, Pepparedsleden 1, Mölndal431 83, Sweden

3. AstraZeneca R&D Lund, Scheelevägen 1, Lund 22187, Sweden

4. Medicinal Chemistry Berlin, Drug Discovery, Pharmaceuticals, Bayer AG, Berlin 13353, Germany

5. AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leicestershire LE11 5RH, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01690

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