Structural and Functional Analysis of Anti-Influenza Activity of 4-, 7-, 8- and 9-Deoxygenated 2,3-Difluoro-N-acetylneuraminic Acid Derivatives-Reference-Cited by-同舟云学术

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Structural and Functional Analysis of Anti-Influenza Activity of 4-, 7-, 8- and 9-Deoxygenated 2,3-Difluoro-N-acetylneuraminic Acid Derivatives

Published:2018-02-03 Issue:5 Volume:61 Page:1921-1933
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

McKimm-Breschkin Jennifer L.¹^ORCID,Barrett Susan¹,Pilling Patricia A.¹,Hader Stefan²,Watts Andrew G.²,Streltsov Victor A.³

Affiliation:

1. CSIRO Manufacturing, 343 Royal Parade, Parkville, Victoria 3052, Australia

2. Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom

3. The Florey Institute of Neuroscience and Mental Health, 30 Royal Parade, Parkville, Victoria 3052, Australia

Funder

Medical Research Council

National Health and Medical Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01467

Reference49 articles.

1. The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor

2. The 2.2 A resolution crystal structure of influenza B neuraminidase and its complex with sialic acid.

3. Three-dimensional structure of the neuraminidase of influenza virus A/Tokyo/3/67 at 2·2 Å resolution

4. Sequence and structure alignment of paramyxovirus hemagglutinin-neuraminidase with influenza virus neuraminidase

5. Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistance

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