Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer’s Disease with Positron Emission Tomography-Reference-Cited by-同舟云学术

Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer’s Disease with Positron Emission Tomography

Published:2017-07-12 Issue:17 Volume:60 Page:7350-7370
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gobbi Luca C.¹^ORCID,Knust Henner¹,Körner Matthias¹,Honer Michael¹,Czech Christian¹,Belli Sara¹,Muri Dieter¹,Edelmann Martin R.¹,Hartung Thomas¹,Erbsmehl Isabella¹,Grall-Ulsemer Sandra¹,Koblet Andreas¹,Rueher Marianne¹,Steiner Sandra¹,Ravert Hayden T.,Mathews William B.,Holt Daniel P.,Kuwabara Hiroto,Valentine Heather,Dannals Robert F.,Wong Dean F.,Borroni Edilio¹

Affiliation:

1. Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00632

Reference50 articles.

1. Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work.

2. The Core of Tau-Paired Helical Filaments Studied by Scanning Transmission Electron Microscopy and Limited Proteolysis

3. Neuropathological stageing of Alzheimer-related changes